Optimal Cardiac Biomarkers

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The page below is a sample from the LabCE course Cardiac Biomarkers (retired 12/6/2013). Access the complete course and earn ASCLS P.A.C.E.-approved continuing education credits by subscribing online.

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Optimal Cardiac Biomarkers

An ideal marker for cardiac disease should have these qualitites:

  • Should be specific to myocardial tissue
  • Be in low concentrations in normal peripheral blood
  • Be rapidly released after myocardial injury
  • Should be detected in low quantities with little interference from like compounds
  • Should remain in circulation for a sufficient length of time for detection
  • The plasma concentration of the marker should be directly related to the extent of injury.
  • The test for the biomarker should be easily automated and relatively inexpensive to run, and results should be obtained rapidly.