Peak and Trough Sampling Times

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Peak and Trough Sampling Times

To assess drug concentrations during the trough phase, blood should be drawn immediately before the next dose.

To assess peak levels, the time for drawing depends on the route of administration:

  • Oral: One hour after drug is taken (assumes a half-life of > two hours)
  • IV: 15-30 minutes after injection/infusion
  • Intramuscular (IM): 30 minutes - one hour after injection