Role of Reference and National Laboratories Within the Laboratory Response Network (LRN)

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The page below is a sample from the LabCE course Preliminary Identification of the Primary Select Agents of Bioterrorism (retired 9/7/2022). Access the complete course and earn ASCLS P.A.C.E.-approved continuing education credits by subscribing online.

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Role of Reference and National Laboratories Within the Laboratory Response Network (LRN)

A reference laboratory within the LRN performs tests to detect and confirm (rule-in) the presence of a threat agent. These laboratories ensure a timely local response in the event of a terrorist incident. Rather than having to rely on confirmation from laboratories at the Centers for Disease Control (CDC), reference laboratories are capable of producing conclusive results. This allows local authorities to respond quickly to emergencies.
A national laboratory is the highest level within the LRN. Examples would include those operated by CDC, the United States Army Medical Research Institute for Infectious Diseases, and the NavalMedicalResearchCenter. These laboratories have very unique resources to handle highly infectious agents and the ability to identify specific agent strains.