HER2 by In Situ Hybridization (ISH) Methods

This version of the course is no longer available.
Need multiple seats for your university or lab? Get a quote
The page below is a sample from the LabCE course . Access the complete course and earn ASCLS P.A.C.E.-approved continuing education credits by subscribing online.

Learn more about (online CE course)
HER2 by In Situ Hybridization (ISH) Methods

All of the following are FDA approved for In Situ testing:
PathVysion HER-2 DNA Probe Kit - Abbott Molecular United States (Des Plaines, Illinois)
Fluorescence in situ hybridization (FISH) assay used to determine HER2 amplification, using the locus specific HER2 probe, which spans HER2 gene and the centromere 17 probe, which hybridizes to the alpha satellite DNA located at the centromere of chromosome.

HER2 FISH pharmDx Kit - Dako Corporate Headquarters (Glostrup, Denmark)
FISH assay used to determine HER2 gene amplification in formalin-fixed, paraffin-embedded (FFPE) breast cancer specimens.

Invitrogen SPoT-Light® HER2-CISH Kit - Life Technologies(Carlsbad, California)
Chromogenic in situ hybridization (CISH) using a DNA probe. Quantifiable results are visualized under a standard brightfield microscope.