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Coagulation Disorders - Inherited
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Coagulation Disorders - Inherited
Inherited disorders are those which are considered to be inborn, and have some familial linkage.
Hemophilia A
is a deficiency of coagulation factor VIII.
It is important to note that Hemophilia A can also be acquired, versus inherited, in cases where patients produce auto-antibodies against factor VIII.
It is the most commonly encountered hereditary based coagulation disorder.
Found more commonly in males, its pattern of inheritance is sex-linked recessive.
This disorder presents clinically with hemorrhagic events ranging in severity from mild to severe. Patients often present with spontaneous bleeding into their joints, a classic symptom of this affliction.
The treatment of Hemophilia A often involves the administration of commercial factor VIII products.
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