An Introduction to the Fundamentals of Coagulation

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An Introduction to the Fundamentals of Coagulation

  • Blood flow is arrested by way of a complex series of interrelated physiological and biochemical processes.
  • There are a wide variety of factors that influence the effectiveness of hemostatic processes including the following:

    1. Type of, and degree of, vessel damage
    2. Ability of vasoconstriction to occur
    3. Availability of platelets & their functionality
    4. Availability of clotting factors & their functionality
    5. Absence of inhibitors & anticoagulants