CBC and RBC morphology

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CBC and RBC morphology

CBC results for patients with Sickle Cell Disease who have a hereditary persistence of fetal hemoglobin (HbS/HPFH) may appear normal or demonstrate a mild to moderate anemia. The CBC and peripheral blood smear for a patient with HbS/HPFH appear below.

Reference intervals may vary between facilities and are dependent on patient age and gender. The reference intervals that are shown below are specific to this case.

Parameter

Patient Result

Reference Interval
White blood cell count (WBC) 6.4 3.8 - 9.8 x 109/L
Red blood cell count (RBC) 4.78 4.50 - 5.90 x 1012/L

Hemoglobin

 11.9 13.8 - 17.2 g/dL
Hematocrit 37.7 41 - 50%
MCV 81 80 - 100 fL
RDW 13.2 12 - 14.6
Platelet count 230 140 - 440 x 109/L