Hemoglobin electrophoresis patterns in Sickle Cell Disorders (acid)

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Hemoglobin electrophoresis patterns in Sickle Cell Disorders (acid)

The following list corresponds to this image of an acid hemoglobin electrophoresis.

Lanes 1 and 2 contain controls ASC and AF (Remember, AF and ASC are labels and do not indicate the order of migration.)

Lanes 3 and 4 (patient 1): Heterozygous Sickle Cell Trait (HbSA) Hb S is approximately 30%

Lanes 5 and 6 (patient 2): Double Heterozygous HbSC Disease (HbSC)

Lanes 7 and 8 (patient 3):Homozygous Sickle Cell Disease (HbSS)
Hb S is 100%

Lanes 9 and 10 (patient 4): Sickle Cell Hemoglobin with Hereditary Persistance of Fetal Hemoglobin. Hb S is approximately 70%; HbF 30%.