Any of three major classes of compounds can be used in the management of pain in sickle cell disease. These compounds include opioid, non-opioid, and adjuvants.
Opioids include codeine, levophanol, morphine, ocycodone, and pethidine, among others.
Non-opioids include salicylates, nonacetylated salicylates, acetic acid derivatives, anthranilic acid derivatives, proprionic acid derivatives, and oxicams.
Adjuvants include anti-convulsants, anti-depressants, anti-histamines, and bensodiazepines.
