All of the following criteria for donor RBC to be used for an exchange transfusion relate to both ABO HDFN and HDFN due to anti-D:Less than or equal to 7 days old (or fresher) Reconstituted with AB FFP CMV negative Negative for hemoglobin S Irradiated

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The page below is a sample from the LabCE course Hemolytic Disease of the Fetus and Newborn (retired 4/6/2020). Access the complete course and earn ASCLS P.A.C.E.-approved continuing education credits by subscribing online.

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All of the following criteria for donor RBC to be used for an exchange transfusion relate to both ABO HDFN and HDFN due to anti-D:

  1. Less than or equal to 7 days old (or fresher)
  2. Reconstituted with AB FFP
  3. CMV negative
  4. Negative for hemoglobin S
  5. Irradiated

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