Clinical Diseases Caused by HPV STI Types

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The page below is a sample from the LabCE course Human Papillomavirus (HPV) and Molecular Diagnostic Testing. Access the complete course and earn ASCLS P.A.C.E.-approved continuing education credits by subscribing online.

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Clinical Diseases Caused by HPV STI Types

Most HPV infections do not cause symptoms or clinical disease. Disease-causing infections develop into lesions that form genital condylomas, precancerous changes on external genitalia, or cervical and other lower genital tract carcinomas.

  • Condyloma acuminata - raised and cauliflower-shaped lesions
  • Condyloma planum - flat and less common lesions
  • High-grade intraepithelial neoplasia - precancerous lesions
  • Cancer - HPV is the causative agent of all cervical cancer and the cause of most vaginal, penile, and anal cancer.

The bar graph on the right illustrates the approximate number of HPV-associated cancer cases that occur yearly according to the CDC. This table can be accessed at:

http://www.cdc.gov/cancer/hpv/statistics/cases.htm. Accessed March 16, 2011.