Inherited disorders are those which are considered to be inborn and have some familial linkage.
Hemophilia A is a deficiency of coagulation factor VIII. It is important to note that Hemophilia A can also be acquired versus inherited in cases where patients produce auto-antibodies against factor VIII. Following are other key points regarding hemophilia A:
- It is the most commonly encountered hereditary coagulation disorder.
- Found more commonly in males, its pattern of inheritance is sex-linked recessive.
- This disorder presents clinically with hemorrhagic events ranging in severity from mild to severe. Patients often present with spontaneous bleeding into their joints, a classic symptom of this affliction.
The treatment of Hemophilia A often involves the administration of commercial factor VIII products.
