Cellular Immunity

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Cellular Immunity

  • Cellular immunity includes delayed hypersentivity reactions, graft rejection, graft-versus-host reactions, defense against intracellular organisms, and probably defense against neoplasms.
  • Cellular immunity is mediated by lymphocytes which we call T-cells.
  • T-cells are so named because they are dependent on the thymus for their production and development.
  • The majority of T-cells are long-lived with an average lifespan of 4.4 years, but it is known that some survive for as long as 20 years or more.
  • T-cells are capable of leaving and re-entering the circulation many times during their long life.
  • T and B cells cannot be differentiated when viewing blood films.
  • They are identified through the use of immunologic cell markers.