Dark Precipitate On The Slide

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Dark Precipitate On The Slide

If the hematoxylin is used beyond its' expiration date or has been improperly stored (excessive heating or freezing) it will show signs of deterioration in the form of black precipitate scattered throughout the section.
Proper storage and attention to expiration dates will prevent this problem. Manufacturers of hematoxylin provide guidelines for storage requirements and shelf-life.