Normal megakaryocytes measure approximately 20-90 µm in diameter and have a multilobed nucleus (please refer to the image on the right).
Dysplastic megakaryocytes are:
- Micro-megakaryocytes: smaller than 20 µm
- Hypolobated megakaryocytes: megakaryocytes with two attached lobes
- Monolobated megakaryocytes: megakaryocytes with a single lobe
- Megakaryocytes with separated nuclei: megakaryocytes with lobes completely separated
Examples of Dysplastic Megakaryocytic Cells:
Hypo-lobated megakaryocyte
Micromegakaryocyte
Megakaryocytes with separated nuclei
Monolobated megakaryocyte