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Review 2
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The page below is a sample from the LabCE course
Case Studies in Clinical Microbiology
. Access the complete course and earn ASCLS P.A.C.E.-approved continuing education credits by subscribing online.
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Review 2
Suppola JP. Kuikka A. Vaara M. Valtonen VV. Comparison of risk factors and outcome in patients with
Enterococcus faecalis
vs
Enterococcus faecium
bacteremia.
Scandinavian Journal of Infectious Diseases. 30(2):153-7, 1998.
The purpose of our study was to determine retrospectively the risk factors for the acquisition of
Enterococcus faecalis
vs
E. faecium
bacteremia, as well as the clinical outcomes of these patients.
62 patients with
Enterococcus faecalis
bacteremia were compared to 31 patients with
E. faecium
bacteremia. Haematologic malignancies, neutropenia, high-risk source and previous use of aminoglycosides, carbapenems, cephalosporins and clindamycin were significantly associated with
E. faecium
bacteremia. Instead, urinary catheterization was found to be related to
Enterococcus faecalis
bacteremia. The mortality rates within 7 d and 30 d were 13% and 27%, respectively, in patients with
E. faecalis
bacteremia and 6% and 29%, respectively, in patients with
E. faecium
bacteremia.
There was no difference in mortality between
E. faecalis
and
E. faecium
bacteremia, nor was there a difference in seriousness of disease at the time of bacteremia. In the subgroups of patients with monomicrobial or clinically significant
E. faecalis
vs
E. faecium
bacteremia, the mortality rates were similar to the results of all subjects.
Our results do not support the theory that
E. faecium
would be a more virulent organism than
E. faecalis.
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