User-Friendly Techniques to Identify Resistance Mechanisms in Gram-Negative Bacilli (by CACMLE) (Online Course)

Paul Schreckenberger, PhD, D(ABMM), F(AAM)

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Continuing Education Credits

Course Outline

  • PowerPoint Slides
      • Author - Paul Schreckenberger, PhD, D(ABMM), F(AAM)
      • Penicillins and Cephalosporins
      • Penicillins: Benzyl-penicillin
      • Penicillins: Methicillin
      • Extended-Spectrum Penicillins and 1st Generation Cephalosporins
      • 2nd, 3rd, & 4th Generation Cephalosporins and Monobactams
      • Cephamycins
      • Carbapenems
      • ESBLs
      • AmpC Beta-lactamases
      • KPCs
      • Extended Spectrum Beta-lactamases - TEM and SHV
      • Extended Spectrum Beta-lactamases - CTX-M and OXA
      • Extended Spectrum Beta-lactamases - Resistance
      • Organisms with Extended Spectrum Beta-lactamases
      • Pitfalls of ESBL Testing - Recommendations
      • Vitek Report: E. coli with ESBL
      • Post-Analytic Comment
      • Vitek Report: ESBL + Klebisella oxytoca
      • MicroScan MIC Panel Results: K. oxytoca with K1 BL
      • AmpC Beta-lactamases: Characteristics
      • AmpC Beta-lactamases: Inducible
      • AmpC Beta-lactamases: Antibiotic Inducer Potential
      • E. cloacae with mutational derepressed AmpC
      • E. cloacae with Mutant Colonies
      • Mutant's Progeny Over-Runs
      • AmpC Beta-Lactamase: Constitutive Production
      • AmpC Beta-Lactamase: Antibiotic Selectors for Mutants
      • Two 10-Disk Plates: E. cloacae with Inducible AmpC & AmpC Derepressed Mutant
      • Inducible Beta-Lactamases: Recommendations
      • Vitek Report: E. coli with AmpC?
      • Amended AST Results for E. cloacae with ESBL
      • Amended AST Report for Chromosomal AmpC that is NOT Suspicous for ESBL
      • Citrobacter freundii with ESBL
      • Ertapenem Etest and Imipenem Disk Test with Break-Through Colonies
      • Case 1: Urine Culture
      • Case 1: Vitek Report
      • Case 1: MIC Results
      • Case 1: 10-Disk Plate
      • Case 1: Modified Hodge Test
      • Case 1
      • Case 1: Class A - KPC
      • Case 2: Blood Culture
      • Case 2: Modified Hodge Test
      • Case 2
      • Case 2: Chromosomal AmpC (Derepressed mutant) + Porin mutation
      • Case 3: Patient History
      • Case 3
      • Case 3: Class A - SME Carbapenemase
      • Case 3: Final Report with Post-Analytic Comment
      • Case 4: Patient History
      • Case 4: Modified Hodge Test
      • Case 4: E. cloacae - MBL Etest, Colistin Disk and Tigecycline Etest
      • Case 4
      • Case 4: Class A - NMC-A Carbapenemase
      • Case 5: Patient History
      • Case 5
      • Case 5
      • Case 5
      • Case 5: Class B - NDM-1 Metallo-Beta-Lactamase
      • Case 5
      • Class D - OXA-48 Carbapenemases
      • Instructions for Completing "Unknown Exercises"
      • Hodge Test Examples
      • 10-Disk Plate Example
      • AST Report Form Example
      • AST Report Form for E. cloacae
      • Answers for Hodge Tests, MBL Etests, and EDTA Disk Tests
      • Unknown #1: AST Results
      • Unknown #2: AST Results
      • Unknown #3: AST Results
      • Unknown #6: AST Results
      • Unknown #11: AST Results
      • Unknown #17: AST Results
      • Unknown #18: AST Results
      • Unknown #20: AST Results
      • Unknown #21: AST Results
      • Unknown #22: AST Results
      • FDA and CLSI (2014) Breakpoints for GNR
      • Reporting Using New CLSI/FDA Breakpoints - Validation Study
      • Reporting Using New CLSI/FDA Breakpoints - Test Isolates for Validation Study
      • Reporting Using New CLSI/FDA Breakpoints - Analysis of Data for Validation Study
      • Reporting Using New CLSI/FDA Breakpoints - Validating Panels

Additional Information

Please download and print the 4 files attached:
  - Phenotypic Detection Antibiotic Resistance - 12 Disk Method
  - LUMC 12 Disk Reporting Form
  - References for ESBL Amp C KPC
  - Homework Assigment - Session #4
   
Before starting this course, review "Phenotypic Detection Antibiotic Resistance - 12 Disk Method"
This procedure will be referenced throughout all 4 Sessions.
 
AFTER you have completed Session #3 and BEFORE you begin Session #4, answer the questions presented on "Homework Assignment - Session #4"   This Assignment is intended to assess your understanding, interpretation and application of the various resistance mechanisms presented in Sessions #1- #3. 




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