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Waterfall Information and Courses from MediaLab, Inc.

These are the MediaLab courses that cover Waterfall and links to relevant pages within the course.

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Fundamentals of Hemostasis
Secondary Hemostasis – The Intrinsic Pathway

Here is where the “cascade” or “waterfall” nomenclature becomes evident as each activated factor triggers the conversion and activation of subsequent factors. Factor XIIa, activated previously, catalyzes the conversion of factor XI into XIa, while in the presence of HMWK. Note: This reaction can occur without HMWK, but will be much slower.

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