CLIA: Chemistry / Urinalysis

Question

Which one of the following statements about acetominophen metabolism is false?

Please select the single best answer

It is metabolized in the kidney

It is largely metabolized in the liver to glucuronide and sulfonate conjugates

A small amount is metabolized via cytochrome oxidase to a reactive benzoquinoneimine intermediate

This intermediate becomes toxic to the liver once tissue glutathione becomes depleted

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