Cell Identification

Table of Conditions

The following table lists the various cell types and macroscopic descriptions of CSF, and the patient conditions that could cause those properties to be present in the patient's CSF:

Predominant Cell Appearance Conditions
lymphs variable; clear - turbid
  • viral meningitis
  • tubercular meningitis
  • multiple sclerosis
  • drug abuse
  • lymphoma
  • leukemia
  • Guillain-BarrĂ© syndrome
  • chronic alcoholism
neutrophils variable; clear - turbid
  • bacterial meningitis
  • mycotic meningitis
  • early tuberculosis
  • hemorrhage
  • cerebral abscess
  • tumors
monocytes variable
  • chronic bacterial meningitis
  • partial treatment of meningitis
  • tumors
macrophages clear - turbid or clear - xanthochromic bloody
  • tuberculosis
  • fungal meningitis
  • following hemorrhage
  • blood contamination
eosinophils variable
  • parasitic meningitis
  • fungal meningitis
  • allergic reaction
    • medications
    • shunts
    • dyes
tumor cells variable
  • metastatic carcinoma
blast cells variable
  • leukemia
  • lymphoma
normal to increased lymphs clear - xanthochromic
  • benign tumor
    • spinal cord
    • brain
ependymal or orchoid cells (often clumped) variable; may be xanthochromic bloody
  • trauma
  • spinal tap

Adapted from Saunders Manual of Clinical Laboratory Science. Craig A. Lehrmann, Ed. WB Saunders, 1998.

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