Important Concepts in Quality Control: Standards and Calibrators

Linearity Example

  • Looking at the example to the right, we can see that the instrument on which we are doing a calibration curve is linear up to 1000 mg/100ml of blood for a particular analyte.
  • Accordingly, we can be fairly certain that any results obtain up to 1000 milligrams are accurate. Above 1000 milligrams our curve begins to bend.
  • This means that any results greater than 1000mg may not reflect a true measurement of the analyte being tested. The specimen must be diluted down to the linear range.

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