Penetration and Infection

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The page below is a sample from the LabCE course HIV: Structure and Replication (retired 2/20/2013). Access the complete course and earn ASCLS P.A.C.E.-approved continuing education credits by subscribing online.

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Penetration and Infection

  • After penetration of the cell membrane by the gp41, the HIV capsid enters the cell's cytoplasm.
  • Next, cellular enzymes strip away the capsid so that the HIV genome is released.
  • Also stripped away are proteins p24 and p17. Protein 24 coats the HIV genome and protein 17 lines the inside of the capsid.