Replication

Proteins Involved in Adsorption

  • The joining of the HIV and the host cell involves a spike on the HIV envelope and a CD4 molecule on the T-lymphocyte, macrophage, or brain cell.
  • The molecule on the HIV spike is called glycoprotein 120 or gp120. The "120" refers to the molecular weight of the glycoprotein.
  • While the CD4 site is important in viral binding, there is evidence that there are other molecules called co-receptors also involved.
  • These molecules are embedded in the membranes of T-lymphocytes, macrophages, and brain cells. In the T-lymphocyte the abbreviated name of the protein molecule is CXCR4.

Earn ASCLS P.A.C.E.® credits for your state clinical laboratory personnel license. Visit LabCE.com for medical laboratory technician continuing education.

HIV: Structure and Replication course details »

Learn more about medical technologist continuing education for MTs, MLTs, and other lab personnel »

Get information on laboratory compliance training for clinical and medical laboratories »