Replication

Adsorption (2)

  • Once the gp120 drops down and binds with CD4 and the co-receptor, the HIV spike is exposed.
  • The spike is a glycoprotein with a molecular weight of 41 Kilodaltons. This gp41 molecule acts much like a spring-loaded lancet.
  • Once triggered into action by the attachment of the gp120 to the CD4 and co-receptor, the gp41 springs out and pierces the membrane of the host cell.

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