Sample Page

Clinically relevant information on D phenotypes can be summarized as follows:

D phenotype	D antigen expression	Rh(D) typing	Produce anti-D	RBC to transfuse	RhIg recommended**
D+	normal	direct agglutination	no	D+ or D–	no
Weak D	normal but weak	IAT	no	D+ or D–	no
Partial D	altered	direct agglutination* & IAT	yes	D–	yes
Partial weak D	altered & variable	direct agglutination* & IAT	yes	D–	yes
D–	none	IAT	yes	D–	yes

* Depending on anti-D reagent used
** USA, UK and parts of Canada