Alveolar Rhabdomyosarcoma (ARMS) in Pleural Fluid

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Alveolar Rhabdomyosarcoma (ARMS) in Pleural Fluid

Metastatic ARMS tumor cells are not as large as adenocarcinoma but will also present in clumps.
Notice the extremely fine chromatin texture and the very large and prominent nucleoli. Several of these tumor cells are bi-nucleate, and a few have very prominent glycogen storage vacuoles in the cytoplasm.