What is Basophilic Stippling?

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What is Basophilic Stippling?

  • On a Wright's-stained smear, the presence of multiple dark blue particles or granules of varying size, scattered throughout the cytoplasm of erythrocytes in the reticulocyte stage is called basophilic stippling.
  • There are two types of stippling, fine or diffuse, and coarse or punctate. The erythrocyte containing them may stain normally in other respects or it may be polychromatophilic.