Sample Question from Erythrocyte Inclusions - Wright Stained Smears, presented by MediaLab

Characteristics of Pappenheimer bodies and Siderotic granules

Siderotic Granules

To verify that red cell inclusions contain iron, it is necessary to use an iron stain, such as Perl's Prussian blue. The iron-containing granules are called siderotic granules.
A mature erythrocyte containing siderotic granules is referred to as a siderocyte, while an immature (nucleated) erythrocyte containing siderotic granules is known as a sideroblast.
A Pappenheimer body is a siderotic granule which is visible on Wright stain.
All Pappenheimer bodies are Prussian blue positive, but not all siderotic granules are visible on Wright's stain as Pappenheimer bodies.

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