Nuclear Variations

Normal Band Forms vs. Pelger-Huet Bands

  • Recognition and diagnosis of the inherited form is important because many of these Pelger-Huet neutrophils may be classified as bands, therefore; increased numbers of bands might be erroneously reported in these patients.
  • Since increased bands frequently indicate infection, reporting Pelger-Huet cells as normal band forms could result in inappropriate treatment for infection.
  • Pelger-Huet bands have more coarse chromatin than normal band forms.

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