When to Suspect an Autoantibody

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When to Suspect an Autoantibody

Autoantibody (Cold or Warm)
Suspect an autoantibody if:
  • All panel and screen cells are positive and auto control is positive.
  • Reaction strength in all the cells will be the same.
Cold autoantibody: strongest reactions occur at immediate spin phase. Reactions may weaken in strength at 37°C and AHG.
Warm autoantibody: strongest reaction occurs at AHG. Reactions may be seen at 37°C and usually not seen at immediate spin.