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Initial Observations of Antibody Panel
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The page below is a sample from the LabCE course
Antibody Detection and Identification (retired 12/6/2013)
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Learn more about Antibody Detection and Identification (retired 12/6/2013) (online CE course)
Initial Observations of Antibody Panel
Look at the phase in which reactions are occurring. Reactions at immediate spin (IS) usually are not clinically significant. Reactions at AHG are clinically significant.
Check for a match in the reactivity pattern by comparing sample reactions and individual antibody reactions
Varying strengths of reactions could indicate dosage. Dosage means that there are two "doses" of the same antigen present on the red cells . Antibodies that exhibit dosage react more strongly with homozygous cells (e.g., Jk
b
Jk
b
) than with heterozygous cells (e.g., Jk
a
Jk
b
) .
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