Initial Observations of Antibody Panel

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Initial Observations of Antibody Panel

  • Look at the phase in which reactions are occurring. Reactions at immediate spin (IS) usually are not clinically significant. Reactions at AHG are clinically significant.
  • Check for a match in the reactivity pattern by comparing sample reactions and individual antibody reactions
  • Varying strengths of reactions could indicate dosage. Dosage means that there are two "doses" of the same antigen present on the red cells . Antibodies that exhibit dosage react more strongly with homozygous cells (e.g., Jkb Jkb ) than with heterozygous cells (e.g., Jka Jkb) .