The virus is spread when body fluids from an individual with the Hepatitis B virus are introduced into the body of a susceptible person.

This contact may occur during introduction of blood or potentially infectious body fluid:

• Through an opening or sore in the skin.
• Via a puncture with a contaminated sharp such as a needle.
• Through direct contact with mucous membranes that line the insides of the mouth, nose, eyes, and the genital organs.

HBV is not spread through casual contact, such as handshake, or through sweat.