Function & Kinetics of Granulocytes

Life Span and function of Eosinophils

  • Eosinophils have a circulating half-life of approximately 18 hours and a tissue life span of at least 6 days.
  • They are capable of locomotion and phagocytosis and can enter inflammatory sites, but do so less readily than neutrophils.
  • In tissues the primary location for eosinophils is in the epithelial barriers to the outside world such as, lungs, skin and GI tract.
  • They are capable of returning to the circulating blood and bone marrow after they enter the tissues.

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