Function and Kinetics of Mononuclear Cells

Cellular Immunity

  • Cellular immunity includes delayed hypersentivity reactions, graft rejection, graft-versus-host reactions, defense against intracellular organisms, and probably defense against neoplasms.
  • Cellular immunity is mediated by lymphocytes which we call T-cells.
  • T-cells are so named because they are dependent on the thymus for their production and development.
  • The majority of T-cells are long-lived with an average lifespan of 4.4 years, but it is known that some survive for as long as 20 years or more.
  • T-cells are capable of leaving and re-entering the circulation many times during their long life.
  • T and B cells cannot be differentiated when viewing blood films.
  • They are identified through the use of immunologic cell markers.

    • Earn ASCLS P.A.C.E.® credits for your AMT, ASCP, or NCA recertification requirements.

    Normal Peripheral Blood Cells course details »

    Learn more about medical technologist continuing education for MTs, MLTs, and other lab personnel »

    Get information on laboratory compliance training for clinical and medical laboratories »