Pharmacogenomics

Question

A patient is taking cimetidine for a stomach ulcer. This drug inhibits CYP2D6. The patient is now prescribed amphetamine for narcolepsy. Amphetamine is metabolized by CYP2D6. What would you predict?

Please select the single best answer

The dose for the amphetamine needs to be lower than normal.

The dose for amphetamine needs to be higher than normal.

Nothing can be assumed until you know the patient's status (PM, EM, UM).

The two drugs can never be given together since they interact.

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