Pharmacogenomics

CYP450s

Many CYP450 enzymes have been characterized, and the substrates (drugs) that each can recognize have been worked out to a large extent.

These subfamilies of CYP450 enzymes have all been associated with polymorphisms that can affect drug disposition: CYP1A2, CYP2C9, CYP2C19 and CYP2D6.


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