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Review 1
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The page below is a sample from the LabCE course
Case Studies in Clinical Microbiology
. Access the complete course and earn ASCLS P.A.C.E.-approved continuing education credits by subscribing online.
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Review 1
Lorimer JW. Eidus LB.: Invasive Clostridium septicum infection in association with colorectal carcinoma.
Canadian Journal of Surgery. 37:245-9, 1994
The association between invasive
Clostridium septicum
infection and colorectal carcinoma is examined by the presentation of three cases and a review of the literature.
In the first two cases the patients presented with nontraumatic metastatic clostridial gas gangrene.
In the third case a patient with chemotherapy-induced myelosuppression from concomitant multiple myeloma had a necrotizing transmural infection of the right colon.
The apparent portal of entry of
Clostridium septicum
was an occult carcinoma of the ascending colon. The increasing evidence for a strong link between this organism and some cases of neutropenic enterocolitis is reviewed.
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