Review 1 from Current Topics in Clinical Microbiology, presented by MediaLab

Acute enteritis with sepsis: Literature Reviews and Queries

Review 1

Lorimer JW. Eidus LB.: Invasive Clostridium septicum infection in association with colorectal carcinoma.
Canadian Journal of Surgery. 37:245-9, 1994
The association between invasive Clostridium septicum infection and colorectal carcinoma is examined by the presentation of three cases and a review of the literature.
In the first two cases the patients presented with nontraumatic metastatic clostridial gas gangrene.
In the third case a patient with chemotherapy-induced myelosuppression from concomitant multiple myeloma had a necrotizing transmural infection of the right colon.
The apparent portal of entry of Clostridium septicum was an occult carcinoma of the ascending colon. The increasing evidence for a strong link between this organism and some cases of neutropenic enterocolitis is reviewed.

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