Erythrocyte Disorders: Smear Case 10: Multiple Erythrocyte Abnormalities

Poikylocytosis and Basophilic Stippling

Poikylocytosis that includes tear-drop shaped erythrocytes, schistocytes, and target cells is present in both the upper and lower photographs.

In addition, macrocytes are present, two of which (one in each field) have coarse basophilic stippling. The stippling may represent abnormal hemoglobin synthesis. These stippled erythrocytes remain in circulation in the absence of pitting by a spleen.

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