Erythrocyte Disorders: Smear Case 10: Multiple Erythrocyte Abnormalities
Many of the distorted erythrocytes displayed on the previous page are also present on this one. We see anisocytosis, poikilocytosis, fragmented forms, target cells, and a few Howell-Jolly bodies.
- Note also circulating nucleated red blood cells (normoblasts).
- The presence of these normoblasts may represent a premature release from a hyperplastic marrow or, more likely, are due to a lessening of the normal inhibition of erythroid release from the marrow as a result of splenectomy, permitting their earlier entry into the circulation.