Erythrocyte Disorders: Smear Case 10: Multiple Erythrocyte Abnormalities

Normoblasts

Many of the distorted erythrocytes displayed on the previous page are also present on this one. We see anisocytosis, poikilocytosis, fragmented forms, target cells, and a few Howell-Jolly bodies.

  • Note also circulating nucleated red blood cells (normoblasts).
  • The presence of these normoblasts may represent a premature release from a hyperplastic marrow or, more likely, are due to a lessening of the normal inhibition of erythroid release from the marrow as a result of splenectomy, permitting their earlier entry into the circulation.

Meet OSHA laboratory safety and compliance requirements with over 40 online courses for clinical laboratories. Learn more.

Red Cell Disorders: Peripheral Blood Clues to Nonneoplastic Conditions course details »

Learn more about laboratory continuing education for ASCP, AMT, NCA, and state renewal and recertification requirements »

Get information on laboratory safety and compliance courses for clinical and medical laboratories »