Erythrocyte Disorders: Smear Case 5: Target Cells and Associated Red Cell Abnormalities
The photograph is representative of the peripheral blood smear of a five-month-old immigrant from Asia. Her mother was concerned that the child was not eating well. Her spleen was palpable.
The hemogram revealed the following:
Hb 9.6g/dL (normal 12.0 - 16.0 g/dL)
RBC 5.48 X 1012/L (normal 4.2 - 5.9 X 1012/L
HCT 30.4% (normal 37 - 48%)
MCV 55.4 fl (normal 86 - 98 fl)
MCH 17.5 pg (normal 27 - 32 pg)
MCHC 31.6 g/dL (normal 31 - 37 g/dL)
RDW 34.9% (normal 11 - 15%)
Reticulocyte count 10.9% (normal 0.5 - 1.5%)
Select the most likely diagnosis based on the clinical information and peripheral blood findings.
Please select the single best answer