An Introduction to the Fundamentals of Coagulation: Coagulation Disorders

Coagulation Disorders - Inherited

  • Hemophilia B is a deficiency of coagulation factor IX.
  • Found almost exclusively in males, its pattern of inheritance is sex-linked recessive.
  • This disorder presents almost identically to Hemophilia A in terms of symptoms, and has a very similar pattern of inheritance.
  • Be sure to keep in mind that while similar, Hemophilia A and B are caused by a deficiency in different coagulation factors.
  • The treatment of Hemophilia B involves therapeutic administration of Factor IX concentrates.

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