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Segmentation Information and Courses from MediaLab, Inc.

These are the MediaLab courses that cover Segmentation and links to relevant pages within the course.

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CLIA Hematology / Hemostasis Review
The WBC indicated by the arrow in this illustration is exhibiting:View Page
Pelger-Huet anomaly is characterized by:View Page

White Cell and Platelet Disorders: Peripheral Blood Clues to Nonneoplastic Conditions
Pelger-Huet Anomaly

The Pelger-Huet anomaly is a congenitally acquired condition of nuclear segmentation and is clinically insignificant. There is no loss of cellular function.The condition can be suspected if typical bilobed, "pince-nez" nuclei are observed (left upper frame in the composite photograph).Band neutrophils usually have two distinct lobes, connected by a relatively short but thick bridge as illustrated in the upper and lower right frames. Monolobated cells may also be encountered, as illustrated in the lower left frame. If these are seen in significant numbers, the possibility of a homozygous Pelger-Huet should be considered.

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