Sclerosis Information and Courses from MediaLab, Inc.
These are the MediaLab courses that cover Sclerosis and links to relevant pages within the course.
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| The image is a stained smear of cerebrospinal fluid. Which of the following statements is true about the cells shown at the right? | View Page |
| Match the condition on the left with associated CSF cells on the right. | View Page |
| Monocytes (continued) Monocytes are also present in this field. Increased numbers of monocytes may be seen in chronic bacterial meningitis, multiple sclerosis, fungal meningitis, CNS malignant disorders or CNS hemorrhage. | View Page |
| Lymphocytes Many lymphocytes are present in this field. Two larger, atypical lymphocytes with intact cytoplasm and slightly indented nuclei are seen near the center of this slide. Two other large cells with irregular, trailing cytoplasm are macrophages (histiocytes). Increased lymphocytes may be seen in viral meningoencephalitis, partially treated bacterial meningitis, multiple sclerosis, Guillian-Barre's syndrome, or polyneuritis.
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| Which of the following conditions is most likely when an oligoclonal band is seen in CSF electrophoresis without a corresponding serum peak? | View Page |
| High Resolution Electrophoresis (HRE) High resolution electrophoresis (HRE) is routine electrophoresis using a high voltage. Serum samples separated with HRE may yield approximately fifteen distinct protein bands. Other HRE applications are the separation of CSF proteins for the diagnosis of multiple sclerosis and light chains in urine for early detection of lymphoproliferative disorders such as multiple myeloma. Both of these specimen separations require more resolution of proteins than routine protein electrophoresis can provide. Increasing the voltage will increase heat generated. To prevent denaturation of proteins, drying out of gels and other system components, a cooling system is included in HRE instrumentation. | View Page |