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Pseudomacrocyte Information and Courses from MediaLab, Inc.

These are the MediaLab courses that cover Pseudomacrocyte and links to relevant pages within the course.

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Red Cell Morphology
Pseudomacrocytes

Another type of macrocyte can be seen in this image. Notice it appears larger than the lymphocyte but in contrast to the macrocytes (megalocytes) seen in megaloblastic anemias (vitamin B12 or folic acid deficiency), these macrocytes have an area of central pallor. These macrocytes are sometimes referred to as "pseudomacrocytes," since their size is the result of exaggerated flattening and thus the presence of central pallor. When this type of macrocyte is present on a blood slide, the MCV will most likely be within normal range. Pseudomacrocytes can be seen in peripheral blood smears from patients with cirrhosis of the liver, obstructive jaundice, post splenectomy and conditions that affect the red cell membrane.

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Pseudomacrocytes

Pseudo macrocytes, as well as some microcytes, can be seen in this slide. Notice that pseudomacrocytes do not have the oval appearance seen in some megalocytes.

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The round and oval red cells with diameters of greater than 9 microns and decreased central pallor seen in this slide are example of:View Page
The cell in the center of this slide would be a:View Page
Summary of Macrocytes

To summarize, two types of macrocytes can be seen, true macrocytes (megalocytes) and pseudomacrocytes. The MCV and MCH values will be increased when megalocytes are present, while all the indice values will be normal when pseudomacrocytes are found.

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All of the following statements are true of "pseudomacrocytes" EXCEPT:View Page


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