Potassium Information and Courses from MediaLab, Inc.
These are the MediaLab courses that cover Potassium and links to relevant pages within the course.
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| Chemical Substances Present in CSF The following table lists some of the chemicals present in CSF, and their concentrations: ChemicalLevel sodium 136.0 - 150.0 m Eq/L potassium 2.3 - 2.7 m Eq/L magnesium2.4 - 3.0 m Eq/Lprotein2 - 4 mg/dL (normally diffuses across blood-brain barrier) glucose 45.0 - 60.0 mg/dL calcium2.1 - 2.7 m Eq/dLcholesterolpresent in small amounts creatinine 0.5 - 1.2 mg/dL lactic acid dehyrdogenase (LDH) present in small amounts phosphorus (inorganic)1.0 - 2.0 mg/dLurea6.0 - 16.0 mg/dL uric acid 0.5 - 3.0 mg/dL | View Page |
| False Negative Results False negative results occur when elements present in the urine interfere with either the enzymatic reaction or prevent the oxidation of potassium iodide. Examples of such substances include: large quantities of ketones aspirin ascorbic acid > 50 mg/dL with some reagent strips levadopa 5-hydroxyindoleacetic acid homogentisic acid sodium fluoride ( a preservative)A specific gravity higher than 1.020 may lower glucose reagent sensitivity, especially in the presence of a high urine pH. Exposing reagent strips to excess humidity may also reduce glucose reagent reactivity.Check the package insert of the reagent strips used in your laboratory for interfering substances that may affect glucose results. | View Page |
| The reagents used in the nitroprusside reaction are: (Choose ALL of the correct answers) | View Page |
| Patients with which of the following conditions would benefit most from washed red cells: | View Page |
| Which of the following analytes would not be significantly increased in a plasma sample as a result of hemolysis: | View Page |
| Which of the following electrolytes is most likely to be spuriously elevated in a hemolyzed specimen: | View Page |
| The most likely cause of an elevated potassium level in an apparently normal individual is: | View Page |
| Which of the following contributes most to serum osmolality: | View Page |
| Which of the following would not be considered a normal part of a routine electrolyte panel: | View Page |
| Which form of hemoglobin cannot be measured using the cyanmethemoglobin method: | View Page |
| JCAHO Sentinel Event ALERTS
Since 1998, JCAHO has issued 25 Sentinel Event ALERTS to the healthcare community. These publications include more than 50 evidence or expert-based recommendations for preventing adverse events.
Sentinel Event Alerts address various error reduction topics:
Transfusion reactionsInpatient suicideInfant abductionsWrong site surgery or other proceduresPatient falls
Laboratory professionals can be involved in all of these types of Sentinel Events.
JCAHO's first Sentinel Event ALERT addressed the common practice of storing concentrated potassium chloride solutions in hospital nursing units.
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| Direct Error Detection
Even perfect systems designs cannot avert human limitations. Medical errors occur and they have to be detected before they can be resolved.
Sometimes people directly observe and immediately report these mistakes. | View Page |
| Types of Medical Errors
Medical errors usually belong to one or more of these categories: | View Page |
| These statements describe sources of laboratory-related errors. | View Page |
| Case Marcie Moore was a phlebotomist at a community hospital in Atlanta. It was her week to collect the pediatric unit and she was on her way to the room of a newborn for which she had just received orders to draw a STAT BMP (chem-7) and bilirubin. After informing the mother of the baby about the test she needed to perform, Marcie set up to perform a heel stick on the baby. Marcie chose a site on the outer edge of the heel on the bottom of the baby’s foot ( the correct area for a heel stick) and made a small incision with a Tenderfoot lancet after cleaning the site well with alcohol.She immediately began collecting the blood in the correct tube for the BMP and bilirubin. Blood flow was not strong so Marcie squeezed the baby’s foot a little to help the blood come out faster – the newborn was screaming and Marcie could tell it was making the mother uncomfortable. She wanted to hurry and get done so the mother could hold the baby.After the chemistry tech ran the blood tests on the tube, she informed Marcie that the newborn had a panic potassium level which did not coincide with the previous blood work on the newborn. Also the chemistry instrument could not perform the bilirubin due to hemolysis. Marcie was asked to recollect the specimen. | View Page |
| Discussion Hemolysis can easily be caused by improper phlebotomy techniques. Hemolysis occurs when RBCs are broken up and hemoglobin is released into the plasma, causing it to become pink rather than its natural straw color. Hemolysis can occur by using too small a needle, pulling a syringe plunger too rapidly, expelling blood vigorously into a tube, or shaking a tube of blood too hard. Hemolysis can cause falsely increased potassium, magnesium, iron, and ammonia levels, and other aberrant lab results.In this case, Marcie did not properly wipe the site with gauze after cleaning it with alcohol, and alcohol contacting the blood could have caused RBCs to break up or hemolyze. Marcie also squeezed the baby’s foot too hard, causing hemolysis.Relevant topics:Site selection and preparation, Heelstick: Puncture, Hemolysis, Causes of hemolysis | View Page |
| Electrolytes panel (Lytes) Blood is tested for the most important electrolytes (salts):
Sodium (Na)
Potassium (K)
Chloride (Cl)
Carbon dioxide (CO2)Can be run on serum or plasma.
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| Green top tubes Contain either sodium or lithium heparin.Used for tests requiring whole blood or plasma such as ammonia or whole blood potassium.
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| Gray top tubes Contain an inhibitor of glycolysis, such as sodium fluoride.May also contain an anticoagulant such as potassium oxalate.
Used for accurate determination of glucose levels.
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| Plasma electrolytes Electrolytes are salts dissolved in water, including:Sodium (Na)
Potassium (K)
Chloride (Cl)
Bicarbonate (CO2).
Calcium (Ca) | View Page |
| Collection tubes Blood may be collected into either:Red top (clot) tubes.Speckle top tubes (serum separator tube).Gray top tubes specifically designed to preserve glucose levels.
Gray top tubes contain additives such as sodium fluoride or potassium oxalate, which prevent metabolism of glucose by blood cells.
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