Physiology Information and Courses from MediaLab, Inc.
These are the MediaLab courses that cover Physiology and links to relevant pages within the course.
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| Lipoprotein Particles Lipid-carrying particles are collectively known as lipoproteins. Lipoproteins are classified according to their densities. The names of these particles, from least to most dense, are: chylomicrons, very-low-density lipoproteins (VLDL), intermediate-density lipoproteins (IDL), low-density lipoproteins (LDL), and high-density lipoproteins (HDL). Most laboratorians are familiar with these particles as many, especially LDL and HDL, are routinely measured in clinical labs. In this course we will not focus on the physiology of all of these particles or the differences between them all. However it is important to understand the basic structure and function of a lipoprotein particle. | View Page |
| Oxidized LDL Physiology Oxidized LDL leads to the release of chemotactic factors from nearby cells; factors which signal leukocytes to migrate to the site. Recall that atherosclerosis is believed to be caused by phagocytic cells such as macrophages, which ingest LDL particles and turn into stationary foam cells. Macrophages have been shown to have increased affinity for oxidized LDL. Thus, oxidation makes LDL more susceptible to phagocytosis and therefore more atherogenic.Since oxidized LDL is more atherogenic than native LDL it makes sense that oxidized LDL may be a cardiovascular risk marker. Indeed, many studies have now correlated increased levels of oxidized LDL with risk of cardiac events. | View Page |
| More on Erythrocyte inclusions The appearance, composition and associated physiology is specific for each type of inclusion. Identification and quantification of these inclusions is important because their presence may indicate an abnormality in the red cell system. Each of the inclusions listed above can be seen in more than one condition. There are erythrocyte inclusions specific to disorders which cannot be seen with either Wright-Giemsa stain or Perls' Prussian blue iron stain.
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| Ergonomics Ergonomics is a scientific discipline that studies human capabilities in relation to work demands. Ergonomics considers many disciplines in its study including psychology, physiology, kinesiology, industrial engineering, anthropometry (the science of human measurement) and biomechanics (the study of muscular activity). | View Page |
| Anatomy & physiology: definitions Anatomy is the branch of science concerned with the study of the structure of the body.
Physiology is the branch of science concerned with the study of the function of the body.
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| Anatomy & physiology: essential to phlebotomy Since phlebotomy involves puncture of the skin (integumentary system) and veins,
(A component of the cardiovascular system), a basic knowledge of the anatomy and physiology of these systems is essential.
Knowledge of blood and its components is also important.
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| Notes about Poikolocytosis Some forms of poikilocytosis represent in vitro artifact rather than being the result of abnormal physiology within the body. Inconsistent terminology also hampers communication about red cell morphology, in that various terms are used to describe the same type of change. Uniform terminology based on Greek roots has been applied in an attempt to provide standardization, although it has not been widely accepted. | View Page |