Phenobarbital Information and Courses from MediaLab, Inc.
These are the MediaLab courses that cover Phenobarbital and links to relevant pages within the course.
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| Which of the following is used primarily for the treatment of manic-depression: | View Page |
| TDM for Anticonvulsants Anticonvulsants typically have narrow therapeutic windows. When levels are too low, the risk for seizure remains present. Drug levels that are too high can depress the central nervous system and may even lead to coma. Examples of anticonvulsants that are monitored by TDM include: Carbamazepine (Tegretol) Valproic acid (Depakene) Phenytoin (Dilantin) Phenobarbital Primidone (Mysoline) | View Page |
| CYP450 Induction and Inhibition CYP450 Inhibitor Inducer CYP1A2 Amiodarone Cimetidine Ciprofloxacin Tobacco CYP2C9 Amiodarone Fluvastatin Isoniazid Fluconazole Rifampin Secobarbital CYP2C19 Cimetidine Indomethacin Ketokonazole Prednisone CYP2D6 Celecoxib Cimetidine Cocaine Methadone Pentazocine Imipramine Desipramine Amitriptyline CYP2E1 Disulfiram Fluoxetine Ethanol Isoniazid CYP3A Midazolam Erythromycin Methadone Phenobarbital Dexamethasone Note: This is not an exhaustive listing of inducers and inhibitors.Reference: Tanaka E, Terada M, Misawa S. Cytochrome P450 2E1: it's clinical and toxicological role. J Clin Pharm Ther. 2000 Jun;25(3):165-75. | View Page |