Pernicious Information and Courses from MediaLab, Inc.
These are the MediaLab courses that cover Pernicious and links to relevant pages within the course.
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| Bence-Jones proteinuria is associated with all of the following conditions except: | View Page |
| Howell-Jolly bodies are composed of: | View Page |
| Eosinophilia is commonly found in which of the following disorder(s): | View Page |
| What are the erythrocyte inclusions that are indicated by the arrows on this blood smear? | View Page |
| A 10-year-old child presents with jaundice and scleral icterus. The photograph captures a section of the peripheral blood smear. The report should direct attention to: | View Page |
| The arrow on this photomicrograh points to a macrocyte. The oval shape should be noted on the patient report. | View Page |
| Another Example of Macrocytosis Another example of macrocytes is seen in this slide. This patient had pernicious anemia, which results from an inability to absorb the vitamin B12 needed for DNA synthesis. Since many cells are destroyed in the bone marrow, decreased numbers of red cells are present in the circulating blood causing low hemoglobin(anemia).
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| Conditions Associated with Hypersegmented Neutrophils There are a number of conditions in which hypersegmented neutrophils may be seen, such as megaloblastic anemias that include folic acid deficiency and pernicious anemia. Individuals who are receiving chemotherapy or have long-term chronic infections may also have hypersegmented neutrophils.The cells seen in these conditions would be classified as pathological since the body is responding abnormally as a result of either a deficiency of a component needed for DNA production or because of the toxic effect that chemotherapy drugs have on DNA. | View Page |