Paternity Information and Courses from MediaLab, Inc.
These are the MediaLab courses that cover Paternity and links to relevant pages within the course.
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| HLA antigen testing may be used for all except the following: | View Page |
| When Nucleic Acids Get Altered The reason to chose a particular molecular method can be influenced by disease detection, monitoring or therapy in certain patient populations. Molecular methodologies can be used to identify alterations or variations or changes in DNA sequencing that can cause disease. Sequence alterations that are known to cause disease are termed mutations. These changes or mutations can be applied to areas of the clinical lab such as infectious disease, paternity, genetic testing, and pharmacogenetics. Some of the more common alterations are:Deletion: a missing nucleotide or other portion of DNA sequence Insertion: an extra DNA nucleotide or other portion of DNA sequence Missense: a nucleotide or sequence substitution that codes for a different amino acidNonsense: a nucleotide substitution that ends in early termination of the protein manufacturing process; usually due to a stop codon.The most common alteration is a single base change or single nucleotide polymorphism (SNP) | View Page |
| Yellow top tubes Contain either acid citrate dextrose (ACD), which maintains RBC viability and may be used for HLA phenotyping, DNA, paternity testing, or lymphocyte surface markers, or:
Sodium polyanetholesulfonate (SPS) which is sometimes used to collect blood culture specimens.
| View Page |
| Importance of Semen Analysis Semen analysis is important for several reasons:To determine whether compromised semen parameters contribute to infertilityTo confirm that vasectomy has reduced sperm count to zeroTo confirm the presence of sperm following reversal of vasectomyTo confirm or refute the presence of sperm in cases where rape is suspected or paternity is in question | View Page |
| Identity of patient When doing a semen analysis it is important to be certain that the patient has been correctly identified prior to collection. At some locations the patient is asked to show a picture ID at the time of collection or when accepting a specimen produced at home.
In situations where rape is suspected or paternity is in question, law enforcement officials should be consulted. It may be necessary for law enforcement officials to be present to identify the patient and to ensure that chain of custody has been correctly established. | View Page |