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Oxyhemoglobin Information and Courses from MediaLab, Inc.

These are the MediaLab courses that cover Oxyhemoglobin and links to relevant pages within the course.

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Cerebrospinal Fluid
An Example of Xanthochromia

Two to four hours after a subarachnoid hemorrhage, the supernatant of a CSF sample will be pale pink to pale orange. The source of this color is oxyhemoglobin from lysed red cells present in the CSF before the puncture. Xanthochromia from the lysed red cells reaches its peak 24 - 36 hours after the hemorrhage and gradually disappears after four to eight days. In the same type of hemorrhage, after 12 hours yellow xanthochromia begins to appear due to the presence of bilirubin. The bilirubin is the breakdown product of oxyhemoglobin from the original lysed red cells. The yellow color in the supernatant reaches its peak in about two to four days and disappears after two to four weeks.

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Other Causes of Xanthochromia

Examples of sources of pigment other than oxyhemoglobin and bilirubin that can cause xanthochromia include: methemoglobinincreased CSF protein (> 150 mg/dL)contamination by skin antiseptic (iodine or merthiolate)

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CLIA General Laboratory Review
Which of the following forms of hemoglobin cannot be detected by routine hemoglobin methods:View Page

CLIA Hematology / Hemostasis Review
Which form of hemoglobin cannot be measured using the cyanmethemoglobin method:View Page


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